Human Sera
Cayman Chemical Coydals ynusuo Coydaln 50mg
A phospholipid found in biological membranes can be used in the generation of liposomes and other artificial membranes
Cayman Chemical RamoplnIn Complex 100mg
An internal standard for the quantification of pravastatin by GC- or LC-MS
Cayman Chemical Cortexolon 17apropIonAT 100mg
A Gardenia extract that contains crocin I II and III and crocetin among other compounds
Cayman Chemical 4MethyLMbelIferyl2ACTAm 100mg
A cholesterol ester that has been found in human meibum can be hydrolyzed by cellular extracts from cultured human skin fibroblasts isolated from healthy individuals but not patients with CESD or Wolman disease
Cayman Chemical 1Stearoyl2Oleoyl3LInoleo 50mg
A cholesterol ester has been used in the generation of nanoparticles and liposomes for drug delivery
Cayman Chemical NalmefenhydrochlorIde 50mg
An insecticide synergist inhibits CYP activity in western corn rootworm abdominal microsomes increases the toxicity of deltamethrin to field-collected deltamethrin-resistant strains of the bed bug C lectularius by 5 6- to 176-fold at 50 g/l increases the toxicity of cyhexatin to fourth instar larvae of susceptible strains of the cotton leafworm S littoralis not toxic to the freshwater invertebrates H azteca C tentans and L variegatus (LC50s 530 2740 and 3540 g/L respectively) and reduces the toxicity of diazinon chlorpyrifos and azinphos-methyl
Cayman Chemical DProPheArgpNAhydrochlor 100mg
An internal standard for the quantification of brexpiprazole by GC- or LC-MS
Cayman Chemical HederagenIn 100mg
A proneurogenic and neuroprotective compound derivative of P7C3 increases proliferation the SGZ of the adult mouse dentate gyrus (0 1-10 UM) decreases contusion volume increases proliferation in the SGZ and improves learning in the Morris water maze (10 mg/kg i p twice daily for one week) prevents or reverses dopaminergic cell death and motor deficits in a 6-OHDA rat model of Parkinsons disease
Cayman Chemical FluphenazIn decnoate 100mg
A dopamine D3 receptor agonist selectively binds to dopamine D3 over dopamine D1 D2 and D4 receptors (Kis 0.14 4600 2.85 and 756 nM respectively) as well as 5-HT1A 5-HT2A 5-HT2B and 5-HT2C (Kis 6 54 1.47 and 252 nM respectively) partial agonist of dopamine D2 receptors (EC50 2.26 nM in a G protein recruitment assay) antagonist of dopamine D3 receptors (IC50 4.62 nM) reduces cocaine self-administration in rats at 3 mg/kg
Cayman Chemical LercnIdIpInhydrochlorIde 100mg
A cationic cholesterol has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability has been used to deliver siRNA into mice via intravenous injection resulting in HAPC-chol accumulation in the lungs
Cayman Chemical RhodIola rosea RosavIn 50mg
A mixture of the cationic lipid isomers DOTMA and N-[1-(23-dielaidoyloxy)propyl]-NNN-trimethylammonium
Cayman Chemical 5 6 7-TrImethoxyflavon 50mg
An active metabolite of nebularine an inhibitor of DNA primase ATP and GTP polymerization activities (IC50s 35 and 28 UM respectively for the human enzyme) and CaMKII (Ki 590 UM)
Cayman Chemical 8 4bromophenyl1 3 5 7tet 100mg
A hydroxyl-terminated PAMAM dendrimer ~30 Å in diameter in PBS and has 32 surface groups an antagonist for PA63 in lipid membranes (IC50 44.9 nM) inhibits amylinS20G aggregation in a concentration-dependent manner inhibits amylinS20G-induced toxicity in MIN6-K8 and NIT-1 cells at 6 UM topical application of PAMAM G3.0 amidoethanol (1 mg/ml) encapsulating dexamethasone increases the levels of dexamethasone in the sclera conjunctiva and cornea in isolated rabbit eyes reduces tail growth in C. riparius larvae and induces DNA damage in C. riparius larval homogenates at 10 or 100 ppm
Cayman Chemical AcetylharpagIde 50mg
An inhibitor of c-Src kinase (IC50 0.01 UM) inhibits phosphorylation of c-Src kinase Lck and c-Yes and VEGFR2 (IC50s 0.01 0.03 0.08 and 0.7 UM respectively) inhibits proliferation of NIH3T3 fibroblasts as well as PC3 DU145 and A549 cancer cells (IC50s 0.5 32 16 and 17 UM respectively) reduces tumor cell proliferation and microvessel density and increases apoptosis in an L3.6pl pancreatic cancer mouse xenograft model at 50 mg/kg per day inhibits tumor growth and metastasis in the same model in combination with gemcitabine
Cayman Chemical Esaxerenon 50mg
A peptide inhibitor of PANX1 inhibits purinergic P2X7 receptor activation-induced dye uptake constitutive dye uptake and hemichannel currents as well as ATP-induced caspase activation and IL-1B release in HEK293 cells at 200 UM inhibits pannexin channel currents and connexin 46 channel currents in Xenopus oocytes expressing the human channels